- Saint Terese
- Salcha
- Salmon Village
- Salt Chuck
- San Juan Cannery
- Sanak
- Savonoski
- Saxton
- Seventeenmile
- Sheldon Point
- Sheldons Point
- Shelton
- Sheshalik
- Shuman House
- Silvertip
- Singeak
- Singigyak
- Sinuk
- Situk
- Skwentina
- Slana
- Slate Creek
- Soldocna
- Sooghmeghat
- Sourdough
- Sourdough Camp
- South Fork
- Spenard
- Squaw Harbor
- Standard
